南京大学：异位甲状腺可保持功能

由于甲状腺的再生仍然具有挑战性，手术切除甲状腺的甲状腺疾病患者必须终生服用激素替代药物。

Since the regeneration of thyroid glands has remained challenging, patients with thyroid disorders who have their glands surgically removed must take hormone replacement medication for the rest of their lives.

来自南京大学的研究者介绍了一种将甲状腺组织块移植到脾脏以再生甲状腺并恢复小鼠甲状腺功能的方法。

Study authors from Nanjing University detail a method involving transplanting blocks of thyroid tissue to the spleen to regenerate thyroid glands and restore full thyroid function in mice.

异位产生的甲状腺仍然完整，可以与周围的脾组织合并，不影响淋巴系统。

An ectopically produced thyroid that is still whole can merge with the splenic tissue around it without affecting its ability to stay separate from the lymphatic system.

这些数据表明，异位甲状腺的功能恢复优于口服左旋甲状腺素治疗的金标准，可以根据身体信号控制激素水平。

The data suggests that the functional restoration by the ectopic thyroid is better than the gold standard of oral levothyroxine treatment for controlling hormone levels in response to body signals.

研究论文发表在《先进科学》杂志上。

The research article was published in Advanced Science.

参考文献：

Tian XJ, Yin ZJ, Li ZJ, Wang ZZ, Xing Z, Liu CY, Wang LT, Wang CM, Zhang JF, Dong L. Regeneration of Thyroid Glands in the Spleen Restores Homeostasis in Thyroidectomy Mice. Adv Sci (Weinh). 2023 Dec 7:e2305913. doi: 10.1002/advs.202305913. Epub ahead of print. PMID: 38059822.